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A new method to monitor drugs at dance venues
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author: John D Ramsey, Marcus A Butcher, Martin F Murphy,

BMJ 2001; 323: 603.

Information on the use of illicit drugs depends heavily on users' recall - what they remember, or think, that they have purchased and on seizures by law enforcement agencies. Neither method may be able to give accurate information on what is currently available. We have developed a new method designed to gain information on current drug consumption in a London dance venue.


UKNEQAS Drugs of Abuse Commentary No. 1, The Effects and Detection of Specimen Dilution
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author: Brian Smith & Steve George

Despite urine having a variable water content, the ingestion of large amounts of fluids will produce a dilute specimen. This is sometimes a deliberate mechanism of avoiding detection of drug misuse since the resultant concentration of any drugs that may be excreted in the urine could be below the sensitivity of the assays used for their detection.


UKNEQAS Drugs of Abuse Commentary No. 2, The Effects of Specimen Adulteration (Nitrite)
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author: Brian Smith & Steve George

The addition of a chemical to a specimen (adulteration) can either chemically modify (destroy) all or some of an analyte, or it can interfere with the analytical method or do both. This has the effect of producing “false negative” results whereby the presence of a drug in a specimen is missed by the testing laboratory.


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